Description

Estradiol 17-Isovalerate is a synthetic, long-acting ester derivative of the natural estrogen, estradiol. This modification enhances its lipophilicity and prolongs its biological activity, making it a valuable intermediate in advanced pharmaceutical synthesis. It is primarily utilized by research institutions and manufacturers in the life sciences sector for the development of hormone therapies and controlled-release formulations. The compound is identified by the CAS registry number 869627-83-8.

Application

• Pharmaceutical Intermediate: Key starting material or intermediate in the synthesis of long-acting estrogenic drugs and hormone replacement therapies (HRT).
• Research & Development: Used in preclinical and clinical research to study estrogen receptor activity, pharmacokinetics, and novel drug delivery systems.
• Veterinary Medicine: Employed in the formulation of estrus synchronization agents and hormonal treatments for livestock and companion animals.
• Controlled-Release Formulations: Serves as an active pharmaceutical ingredient (API) in the development of implants, injectable depots, and transdermal patches due to its esterified, slow-release properties.
• Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation of related steroid compounds.

Basic Information

Product Name	Estradiol 17-Isovalerate
CAS No.	869627-83-8
Molecular Formula	C24H34O3
Molecular Weight	370.53 g/mol
Synonyms	Estradiol 17-Valerate; 17β-Estradiol 17-valerate; Oestradiol Valerate; Estradiol Valerate; Estra-1,3,5(10)-triene-3,17β-diol 17-valerate; 3,17β-Dihydroxyestra-1,3,5(10)-trien-17-yl pentanoate; NSC 17591; Valerate ester of estradiol
EINECS	Contact for details

Quality Control

Our Estradiol 17-Isovalerate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and residual solvent analysis. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with relevant research and pharmaceutical intermediate standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.