Description

tert-Butyl (2-[(3-Iodopyridin-2-Yl)Thio]Ethyl)Carbamate is a high-purity, advanced pharmaceutical intermediate featuring a unique pyridine-thioether-carbamate structure. This compound is critical for enabling complex synthetic routes in medicinal chemistry, particularly in the development of targeted small-molecule therapeutics. It is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of novel drug candidates, especially those targeting kinase inhibition and other protein-protein interactions.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of active pharmaceutical ingredients (APIs) for preclinical and clinical research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new drug discovery programs.
• Kinase Inhibitor Development: Serves as a core scaffold or precursor in the synthesis of potential kinase inhibitors due to its heterocyclic structure.
• Peptidomimetic Synthesis: The carbamate-protected amine functionality makes it valuable for constructing peptide-like molecules and prodrugs.
• Chemical Biology Probes: Utilized in the creation of chemical probes for studying biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP or research-grade conditions.

Basic Information

Product Name	tert-Butyl (2-[(3-Iodopyridin-2-Yl)Thio]Ethyl)Carbamate
CAS No.	869567-97-5
Molecular Formula	C12H17IN2O2S
Molecular Weight	380.25 g/mol
Synonyms	Boc-NH-(CH2)2-S-2-Pyridine(I-3); tert-Butyl N-[2-[(3-iodopyridin-2-yl)sulfanyl]ethyl]carbamate; 2-[(3-Iodopyridin-2-yl)thio]ethylcarbamic Acid tert-Butyl Ester; 869567-97-5; N-Boc-2-((3-iodopyridin-2-yl)thio)ethanamine; N-(tert-Butoxycarbonyl)-2-((3-iodopyridin-2-yl)thio)ethanamine; 2-((3-Iodo-2-pyridyl)thio)ethylcarbamic Acid tert-Butyl Ester
EINECS	Contact for details

Quality Control

Every batch of tert-Butyl (2-[(3-Iodopyridin-2-Yl)Thio]Ethyl)Carbamate is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure identity, purity, and consistency for your critical research and development applications. Certificates of Analysis (COA) detailing purity (typically >95% to >98% by HPLC), identity confirmation, and impurity profiles are available for all shipments. Our quality commitment supports compliance with the standards required for pharmaceutical R&D.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This material is light-sensitive and should be handled under appropriate conditions to maintain stability. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.