Description

1-tert-Butyl 2-Methyl 5-Oxopiperidine-1,2-Dicarboxylate is a high-purity, protected piperidine derivative serving as a critical synthetic intermediate in advanced organic chemistry. Its primary value lies in enabling the controlled synthesis of complex nitrogen-containing heterocycles, which are core scaffolds in modern pharmaceuticals. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries, particularly for constructing novel active pharmaceutical ingredients (APIs) and other bioactive molecules.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of piperidine-based drug candidates targeting central nervous system (CNS) disorders, pain management, and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, where the piperidine moiety contributes to biological activity.
• Fine Chemical Production: Serves as a versatile precursor in the multi-step synthesis of complex, high-value specialty chemicals and catalysts.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development and the exploration of new chemical spaces in medicinal chemistry.
• Peptidomimetic Research: Facilitates the construction of peptidomimetics and conformationally restricted peptide analogs for drug discovery programs.
• Chemical Library Development: A valuable scaffold for generating diverse compound libraries used in high-throughput screening (HTS) for lead identification.

Basic Information

Product Name	1-tert-Butyl 2-Methyl 5-Oxopiperidine-1,2-Dicarboxylate
CAS No.	869564-40-9
Molecular Formula	C13H21NO5
Molecular Weight	271.31 g/mol
Synonyms	5-Oxo-1-piperidinecarboxylic acid 1-(1,1-dimethylethyl) 2-methyl ester; 1-(tert-Butoxycarbonyl)-2-(methoxycarbonyl)-5-oxopiperidine; 1-Boc-2-(methyloxycarbonyl)piperidin-5-one; Methyl 1-(tert-butoxycarbonyl)-5-oxopiperidine-2-carboxylate; 5-Oxopiperidine-1,2-dicarboxylic acid 1-tert-butyl 2-methyl ester; 1-N-Boc-2-methyl 5-oxopiperidine-1,2-dicarboxylate; tert-Butyl methyl 5-oxopiperidine-1,2-dicarboxylate
EINECS	Contact for details

Quality Control

Our 1-tert-Butyl 2-Methyl 5-Oxopiperidine-1,2-Dicarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specification results. Our quality commitment supports applications requiring high-purity intermediates under GMP or ISO-guided environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.