Description

Methyl 5-Bromo-2-Chloro-1,6-Dihydro-1-Methyl-6-Oxopyridine-3-Carboxylate is a high-purity, advanced pharmaceutical intermediate with a distinct halogenated pyridone structure. This compound matters for its critical role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in medicinal chemistry research and development. Pharmaceutical, agrochemical, and specialty chemical manufacturers need this precise intermediate to enable the efficient and scalable production of novel therapeutic candidates.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging its halogenated heterocyclic core.
• Chemical Biology Probes: Employed in the creation of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects and scale-up processes under cGMP conditions.
• Academic & Industrial R&D: Utilized in academic laboratories and industrial R&D centers for developing new synthetic methodologies and novel compounds.

Basic Information

Product Name	Methyl 5-Bromo-2-Chloro-1,6-Dihydro-1-Methyl-6-Oxopyridine-3-Carboxylate
CAS No.	869357-63-1
Molecular Formula	C8H7BrClNO3
Molecular Weight	280.50 g/mol
Synonyms	Methyl 5-bromo-2-chloro-1-methyl-6-oxo-1,6-dihydropyridine-3-carboxylate; 5-Bromo-2-chloro-1-methyl-6-oxo-1,6-dihydropyridine-3-carboxylic acid methyl ester; 3-Pyridinecarboxylic acid, 5-bromo-2-chloro-1,6-dihydro-1-methyl-6-oxo-, methyl ester; 869357-63-1; Methyl 5-bromo-2-chloro-1-methyl-6-oxo-1,4-dihydropyridine-3-carboxylate
EINECS	Contact for details

Quality Control

Our Methyl 5-Bromo-2-Chloro-1,6-Dihydro-1-Methyl-6-Oxopyridine-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.