Description

4-Chloro-3-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine is a high-value, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in the unique combination of a pyrrolopyridine scaffold with chloro and trifluoromethyl substituents, offering versatile reactivity for constructing complex molecular architectures. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in kinase inhibitor research and other targeted therapies.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging the biological activity of the pyrrolopyridine core.
• Material Science Research: Serves as a precursor for the synthesis of specialized organic electronic materials and ligands for catalysis.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring functionalized nitrogen heterocycles.

Basic Information

Product Name	4-Chloro-3-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine
CAS No.	869335-75-1
Molecular Formula	C8H4ClF3N2
Molecular Weight	220.58 g/mol
Synonyms	4-Chloro-3-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine; 4-Chloro-3-(trifluoromethyl)-7-azaindole; 4-Chloro-3-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine, 4-chloro-3-(trifluoromethyl)-; 869335-75-1; 4-Chloro-3-trifluoromethyl-1H-pyrrolo[2,3-b]pyridine
EINECS	Contact for details

Quality Control

Our production of 4-Chloro-3-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, NMR, and GC-MS to confirm identity and quantify impurities. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.