Description

1H-Pyrrolo[2,3-B]Pyridine, 4-Chloro-3-Fluoro-1-[(4-Methylphenyl)Sulfonyl]- is a high-purity, advanced pharmaceutical intermediate with a defined molecular structure. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers for its role as a key building block in drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of complex drug molecules, particularly those targeting kinase inhibition.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Active Pharmaceutical Ingredient (API) Development: A key building block in the multi-step synthesis of potential new therapeutic agents.
• Biochemical Tool Compound: May be utilized in biochemical assays to study specific biological pathways and protein interactions.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.

Basic Information

Product Name	1H-Pyrrolo[2,3-B]Pyridine, 4-Chloro-3-Fluoro-1-[(4-Methylphenyl)Sulfonyl]-
CAS No.	869335-69-3
Molecular Formula	C14H10ClFN2O2S
Molecular Weight	324.76 g/mol
Synonyms	4-Chloro-3-fluoro-1-[(4-methylphenyl)sulfonyl]-1H-pyrrolo[2,3-b]pyridine; 4-Chloro-3-fluoro-1-(p-tolylsulfonyl)-1H-pyrrolo[2,3-b]pyridine; 1-(4-Methylbenzenesulfonyl)-4-chloro-3-fluoro-1H-pyrrolo[2,3-b]pyridine; 4-Chloro-3-fluoro-1-tosyl-1H-pyrrolo[2,3-b]pyridine; 869335-69-3; Tosyl-protected 4-chloro-3-fluoro-7-azaindole
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[2,3-B]Pyridine, 4-Chloro-3-Fluoro-1-[(4-Methylphenyl)Sulfonyl]- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.