Description

1H-Pyrrolo[2,3-B]Pyridine, 3-Bromo-5-Chloro- is a high-purity halogenated heterocyclic building block of significant importance in advanced organic synthesis. This compound serves as a critical intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of kinase inhibitors and other small molecule drug candidates.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides with specific biological activity.
• Material Science: Serves as a precursor for organic electronic materials, such as those used in OLEDs and semiconductors.
• Chemical Biology: Employed in the design and synthesis of molecular probes and tool compounds for biological target validation.
• Cross-Coupling Reactions: The bromo and chloro substituents make it a versatile substrate for Suzuki, Stille, and Buchwald-Hartwig amination reactions.
• Library Synthesis: A valuable scaffold for generating diverse compound libraries in high-throughput screening and medicinal chemistry programs.

Basic Information

Product Name	1H-Pyrrolo[2,3-B]Pyridine, 3-Bromo-5-Chloro-
CAS No.	869335-36-4
Molecular Formula	C7H4BrClN2
Molecular Weight	231.48 g/mol
Synonyms	3-Bromo-5-chloro-1H-pyrrolo[2,3-b]pyridine; 3-Bromo-5-chloro-7-azaindole; 5-Chloro-3-bromo-1H-pyrrolo[2,3-b]pyridine; 5-Chloro-3-bromo-7-azaindole; 1H-Pyrrolo[2,3-b]pyridine, 3-bromo-5-chloro-; 3-Bromo-5-chloro-1H-7-azaindole; 869335-36-4; 3-Br-5-Cl-7-azaindole
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[2,3-B]Pyridine, 3-Bromo-5-Chloro- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent lot-to-lot quality suitable for demanding research applications. Certificates of Analysis (COA) with full characterization data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is light-sensitive and should be handled under an inert atmosphere when appropriate for prolonged use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.