Description

2-(Tetrahydro-2H-Pyran-4-Yloxy)Isonicotinonitrile is a high-value pharmaceutical intermediate and versatile chemical building block. This compound is critical for the synthesis of complex molecules, offering a unique pyranyloxy-substituted pyridine core that enables specific structural modifications. It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and fine chemical industries for creating novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, where its heterocyclic structure can contribute to new modes of action.
• Ligand Synthesis: Serves as a precursor for creating specialized ligands used in catalysis and material science applications.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis to introduce the tetrahydro-2H-pyran-4-yloxy functional group into more complex molecular architectures.
• Academic & Industrial R&D: A valuable reagent for chemical libraries and exploratory research in universities and corporate R&D laboratories.

Basic Information

Product Name	2-(Tetrahydro-2H-Pyran-4-Yloxy)Isonicotinonitrile
CAS No.	869299-33-2
Molecular Formula	C11H12N2O2
Molecular Weight	204.23 g/mol
Synonyms	4-Pyridinecarbonitrile, 2-[(tetrahydro-2H-pyran-4-yl)oxy]-; 2-(Oxan-4-yloxy)pyridine-4-carbonitrile; 2-(Tetrahydro-2H-pyran-4-yloxy)isonicotinonitrile; 2-(Tetrahydropyran-4-yloxy)isonicotinonitrile; 2-(Tetrahydro-2H-pyran-4-yloxy)-4-cyanopyridine; Isonicotinonitrile, 2-(tetrahydro-2H-pyran-4-yloxy)-; 869299-33-2
EINECS	Contact for details

Quality Control

Our 2-(Tetrahydro-2H-Pyran-4-Yloxy)Isonicotinonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥97.0%
Purity (HPLC, Area%)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.