Description

1,2,3-Trifluoro-5-isocyanatobenzene is a high-value, fluorinated aromatic isocyanate building block essential for advanced material synthesis. Its unique trifluorinated aromatic core imparts exceptional chemical stability, lipophilicity, and electronic properties to final products. This compound is critically needed by R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty polymer industries for developing novel active ingredients and high-performance materials.

Application

• Pharmaceutical Intermediates: Key building block for synthesizing novel drug candidates, particularly in kinase inhibitor and CNS-active molecule research, where the trifluoromethyl and isocyanate groups are leveraged for bioactivity and metabolic stability.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the fluorine atoms enhance compound penetration, environmental persistence, and target binding affinity.
• Specialty Polymers & Resins: Serves as a monomer for producing polyurethanes and polyurea coatings with enhanced chemical resistance, thermal stability, and low surface energy for demanding industrial and electronic applications.
• Liquid Crystal & OLED Materials: Acts as a precursor for fluorinated components in electronic display materials, improving charge transport, solubility, and overall device performance.
• Cross-linking Agent: Utilized to modify surfaces or create cross-linked networks in advanced composites, adhesives, and encapsulants, providing superior durability.
• Organic Synthesis Reagent: A versatile reagent for introducing the phenyl isocyanate moiety into complex molecules via urea or carbamate formation under mild conditions.

Basic Information

Item	Detail
Product Name	1,2,3-Trifluoro-5-isocyanatobenzene
CAS No.	869285-47-2
Molecular Formula	C7H2F3NO
Molecular Weight	179.09 g/mol
Synonyms	5-Isocyanato-1,2,3-trifluorobenzene; 1,2,3-Trifluorophenyl-5-isocyanate; 3,4,5-Trifluorophenyl isocyanate; 869285-47-2; Trifluorinated phenyl isocyanate; Aromatic trifluoro isocyanate
EINECS	Contact for details

Quality Control

Every batch of our 1,2,3-Trifluoro-5-isocyanatobenzene is manufactured and tested under strict quality management systems. We guarantee high purity and batch-to-batch consistency through rigorous analytical protocols including HPLC, GC, and NMR. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to ensure it meets your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is moisture-sensitive and reacts with strong bases; ensure the container is kept sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent hydrolysis and polymerization.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.