Description

(R)-α-Benzyl-Pro Methyl Ester Hydrochloride is a high-purity chiral building block and intermediate of significant importance in advanced organic synthesis. Its defined stereochemistry makes it a critical precursor for the development of enantiomerically pure pharmaceuticals and bioactive compounds. This material is essential for research and production chemists in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce specific chiral centers into complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting neurological and cardiovascular conditions.
• Peptidomimetics Research: Used in the design and construction of peptide analogs and protease inhibitors due to its proline-derived structure.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for synthesizing novel chiral ligands and organocatalysts.
• Agrochemical Synthesis: Employed in the production of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Academic & R&D Laboratories: Utilized in methodological development and medicinal chemistry programs for exploring new synthetic routes.
• Fine Chemical Production: Integral to the manufacture of specialty chemicals requiring high stereochemical fidelity.

Basic Information

Product Name	(R)-α-Benzyl-Pro Methyl Ester Hydrochloride
CAS No.	869001-80-9
Molecular Formula	C14H19NO2·HCl
Molecular Weight	269.77 g/mol
Synonyms	(R)-α-Benzylproline Methyl Ester Hydrochloride; Methyl (R)-(-)-α-benzylprolinate hydrochloride; (R)-1-Benzyl-2-pyrrolidinecarboxylic Acid Methyl Ester Hydrochloride; (R)-α-Benzyl-Pro-OMe·HCl; (R)-N-Benzylproline Methyl Ester Hydrochloride; (R)-Benzyl Proline Methyl Ester HCl; (R)-Proline, 1-benzyl-, methyl ester, hydrochloride
EINECS	Contact for details

Quality Control

Every batch of (R)-α-Benzyl-Pro Methyl Ester Hydrochloride is manufactured under strict quality management systems. Our products undergo rigorous quality testing, including chiral purity verification by HPLC, to ensure compliance with industry standards for advanced intermediates. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your regulatory and R&D needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.