Description

3-Cyano-4-(5,5-Dimethyl-[1,3,2]Dioxaborinan-2-Yl)-Pyridine is a high-value, multi-functional heterocyclic building block that serves as a critical intermediate in modern synthetic chemistry. Its core value lies in the unique combination of a pyridine core, a cyano group, and a protected boronic ester, enabling precise cross-coupling reactions and the construction of complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-purity intermediates for drug discovery, catalyst development, and functional polymer synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Suzuki-Miyaura Cross-Coupling Reactions: The protected boronic ester functionality makes it an ideal, stable coupling partner for constructing biaryl and heterobiaryl systems under mild conditions.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides that require specific heterocyclic scaffolds.
• Ligand and Catalyst Synthesis: Serves as a starting material for creating novel chelating ligands and organometallic catalysts used in asymmetric synthesis.
• Material Science & OLED Development: Employed in the synthesis of electron-transport materials and emissive layer components for organic light-emitting diodes (OLEDs).
• Chemical Biology & Probe Development: Useful for creating fluorescent probes or affinity tags due to its modifiable pyridine and cyano groups.

Basic Information

Product Name	3-Cyano-4-(5,5-Dimethyl-[1,3,2]Dioxaborinan-2-Yl)-Pyridine
CAS No.	868944-73-4
Molecular Formula	C11H13BN2O2
Molecular Weight	216.05 g/mol
Synonyms	4-(5,5-Dimethyl-1,3,2-dioxaborinan-2-yl)-3-pyridinecarbonitrile; 3-Pyridinecarbonitrile, 4-(5,5-dimethyl-1,3,2-dioxaborinan-2-yl)-; 4-(5,5-Dimethyl-1,3,2-dioxaborinan-2-yl)nicotinonitrile; 2-(3-Cyanopyridin-4-yl)-5,5-dimethyl-1,3,2-dioxaborinane; 3-Cyano-4-(5,5-dimethyl-1,3,2-dioxaborinan-2-yl)pyridine
EINECS	Contact for details

Quality Control

Our 3-Cyano-4-(5,5-Dimethyl-[1,3,2]Dioxaborinan-2-Yl)-Pyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Optimal storage temperature is between 2°C and 8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.