Description

tert-Butyl 6-(Hydroxymethyl)Picolinate is a high-purity, versatile chemical intermediate characterized by its picolinate ester structure with a hydroxymethyl functional group. This compound is of significant value in pharmaceutical and agrochemical research for its role as a key building block in the synthesis of complex molecules. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, fine chemical, and agrochemical industries for constructing active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting neurological and oncological pathways.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, leveraging its picolinate core for bioactivity.
• Ligand Precursor: Serves as a starting material for the preparation of specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals and performance materials.
• Academic & Industrial R&D: Essential for research in organic synthesis methodologies and the development of new chemical entities in university and corporate laboratories.

Basic Information

Product Name	tert-Butyl 6-(Hydroxymethyl)Picolinate
CAS No.	868769-75-9
Molecular Formula	C11H15NO3
Molecular Weight	209.24 g/mol
Synonyms	6-(Hydroxymethyl)picolinic acid tert-butyl ester; 2-Pyridinecarboxylic acid, 6-(hydroxymethyl)-, 1,1-dimethylethyl ester; tert-Butyl 6-(hydroxymethyl)pyridine-2-carboxylate; 2-(tert-Butoxycarbonyl)-6-(hydroxymethyl)pyridine; TBHP; 868769-75-9
EINECS	Contact for details

Quality Control

Every batch of tert-Butyl 6-(Hydroxymethyl)Picolinate is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure it meets the high standards required for advanced synthetic applications. Our products are supported by comprehensive Certificates of Analysis (COA) that detail purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to ensure consistency and reliability for our global customer base in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.