Description

tert-Butyl (4-Chloro-3-Formylpyridin-2-Yl)Carbamate is a high-purity, advanced pharmaceutical intermediate characterized by its distinct pyridine core with chloro and formyl substituents. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of complex molecules with targeted biological activity. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in developing novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Agrochemical Synthesis: Serves as a building block for creating novel pesticides and herbicides with specific modes of action.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic Research: Employed in university and institutional labs for methodological development and novel heterocyclic chemistry.

Basic Information

Product Name	tert-Butyl (4-Chloro-3-Formylpyridin-2-Yl)Carbamate
CAS No.	868736-42-9
Molecular Formula	C11H13ClN2O3
Molecular Weight	256.69 g/mol
Synonyms	tert-Butyl N-(4-chloro-3-formyl-2-pyridinyl)carbamate; 2-[[(1,1-Dimethylethoxy)carbonyl]amino]-4-chloro-3-pyridinecarboxaldehyde; 4-Chloro-3-formylpyridin-2-yl-carbamic acid tert-butyl ester; Boc-4-Chloro-3-formyl-2-aminopyridine; (4-Chloro-3-formyl-pyridin-2-yl)-carbamic acid tert-butyl ester; tert-Butyl (4-chloro-3-formyl-2-pyridinyl)carbamate; 2-(tert-Butoxycarbonylamino)-4-chloro-3-pyridinecarboxaldehyde
EINECS	Contact for details

Quality Control

Our tert-Butyl (4-Chloro-3-Formylpyridin-2-Yl)Carbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere such as nitrogen or argon for long-term storage. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.