Description

tert-Butyl 4-Chloro-3-Iodopyridin-2-Ylcarbamate is a high-purity, multi-functional chemical building block designed for advanced synthetic applications. This compound is valued for its role as a key intermediate in the development of complex molecules, particularly in pharmaceutical research and agrochemical synthesis. It is primarily sought after by R&D chemists and process development scientists in the life sciences sector for constructing novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, leveraging its halogenated pyridine core.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemistry, enabling structure-activity relationship (SAR) studies and lead optimization.
• Material Science Precursor: Potential use in the synthesis of specialized ligands, catalysts, or functionalized polymers for advanced materials.
• Cross-Coupling Reactions: The iodine and chlorine substituents make it an excellent substrate for various palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira).

Basic Information

Product Name	tert-Butyl 4-Chloro-3-Iodopyridin-2-Ylcarbamate
CAS No.	868733-96-4
Molecular Formula	C10H12ClIN2O2
Molecular Weight	354.57 g/mol
Synonyms	tert-Butyl N-(4-chloro-3-iodopyridin-2-yl)carbamate; 2-Pyridinecarboxamide, 4-chloro-3-iodo-N-(1,1-dimethylethyl)-; 4-Chloro-3-iodo-N-(tert-butoxycarbonyl)pyridin-2-amine; 4-Chloro-3-iodopyridin-2-ylcarbamic acid tert-butyl ester; BOC-4-Chloro-3-iodopyridin-2-amine; tert-Butyl (4-chloro-3-iodopyridin-2-yl)carbamate; 868733-96-4
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-Chloro-3-Iodopyridin-2-Ylcarbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥97.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.