Description

4-(4-Amino-2-Fluorophenoxy)-Picolinamide is a high-purity organic intermediate with a distinct molecular structure featuring both picolinamide and fluorinated phenoxy moieties. This compound is critical for the synthesis of advanced pharmaceutical agents and agrochemicals, where its specific scaffold enables precise biological activity. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel small-molecule drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Research: Used in the development of next-generation herbicides and fungicides, leveraging its fluorinated aromatic structure.
• Chemical Biology Probe Synthesis: Serves as a precursor for creating molecular probes to study enzyme function and biological pathways.
• Material Science: Potential monomer or additive in the research of specialty polymers with specific optical or electronic properties.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations for custom synthesis and process scale-up projects.

Basic Information

Product Name	4-(4-Amino-2-Fluorophenoxy)-Picolinamide
CAS No.	868733-71-5
Molecular Formula	C₁₂H₁₀FN₃O₂
Molecular Weight	247.23 g/mol
Synonyms	4-(4-Amino-2-fluorophenoxy)pyridine-2-carboxamide; 2-Pyridinecarboxamide, 4-[(4-amino-2-fluorophenyl)oxy]-; 4-[(4-Amino-2-fluorophenoxy)]picolinamide; Picolinamide, 4-(4-amino-2-fluorophenoxy)-; 868733-71-5; FC-APPA; AFPP
EINECS	Contact for details

Quality Control

Every batch of 4-(4-Amino-2-Fluorophenoxy)-Picolinamide is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed chromatographic data are provided for traceability and to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.