Description

1,8-Naphthyridine, 5-Azido-2-Methyl-6-(Phenylmethyl)- is a specialized heterocyclic organic compound featuring a naphthyridine core functionalized with an azido group and a benzyl substituent. This unique structure makes it a valuable high-purity building block for advanced chemical synthesis, particularly in the development of novel pharmacologically active molecules. It is primarily sought by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, especially those targeting neurological or infectious diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides due to its bioactive naphthyridine scaffold.
• Click Chemistry Reagent: The azido (-N3) group enables its use in copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions for bioconjugation and polymer chemistry.
• Ligand Synthesis: Acts as a starting material for creating novel chelating ligands used in catalysis or metal-organic frameworks (MOFs).
• Fluorescent Probe Development: The conjugated system can be utilized to develop fluorescent markers or sensors for biological imaging.
• Academic & Contract Research: Employed in university and CRO laboratories for fundamental organic chemistry research and method development.

Basic Information

Item	Details
Product Name	1,8-Naphthyridine, 5-Azido-2-Methyl-6-(Phenylmethyl)-
CAS No.	868695-86-7
Molecular Formula	C16H13N5
Molecular Weight	275.31 g/mol
Synonyms	5-Azido-2-methyl-6-(phenylmethyl)-1,8-naphthyridine; 5-Azido-2-methyl-6-benzyl-1,8-naphthyridine; 6-Benzyl-5-azido-2-methyl-1,8-naphthyridine; 2-Methyl-6-benzyl-1,8-naphthyridin-5-yl azide; 1,8-Naphthyridine, 5-azido-2-methyl-6-(phenylmethyl)-; Azido-functionalized 1,8-naphthyridine derivative
EINECS	Contact for details

Quality Control

Our 1,8-Naphthyridine derivative is manufactured under controlled conditions to ensure batch-to-batch consistency and high chemical purity. Every lot undergoes rigorous analytical testing including HPLC, NMR, and mass spectrometry to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its light-sensitive nature and propensity for oxidation, it is recommended to handle under an inert atmosphere for long-term storage and to minimize exposure to air and moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.