Description

2-Methyl-2-(4-(5-(Trifluoromethyl)Pyridin-2-Yl)Piperazin-1-Yl)Propanoic Acid is a high-value, non-natural amino acid derivative featuring a piperazine linker and a trifluoromethylpyridine moiety, making it a critical building block in modern synthetic chemistry. Its primary value lies in its role as a sophisticated pharmaceutical intermediate for the research and development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to incorporate its unique structural and physicochemical properties into new molecular entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially for central nervous system (CNS) and oncology targets.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its piperazine and trifluoromethyl groups, which can enhance bioavailability and metabolic stability.
• Agrochemical Synthesis: Serves as a building block for developing advanced pesticides and herbicides with improved efficacy.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring complex heterocyclic compounds.
• Advanced Material Precursors: Potential use in synthesizing specialty polymers or ligands for catalytic systems.

Basic Information

Product Name	2-Methyl-2-(4-(5-(Trifluoromethyl)Pyridin-2-Yl)Piperazin-1-Yl)Propanoic Acid
CAS No.	868604-86-8
Molecular Formula	C14H18F3N3O2
Molecular Weight	317.31 g/mol
Synonyms	2-Methyl-2-[4-[5-(trifluoromethyl)-2-pyridyl]piperazin-1-yl]propanoic acid; 2-Methyl-2-(4-(5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)propionic acid; 868604-86-8; UNII-2Q2S717P0I; 2Q2S717P0I; AOB67717; BDBM50388879; AKOS025147065; ZINC000004259964; SCHEMBL15507711; DTXSID60654588
EINECS	Contact for details

Quality Control

Our production of 2-Methyl-2-(4-(5-(Trifluoromethyl)Pyridin-2-Yl)Piperazin-1-Yl)Propanoic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity, critical for pharmaceutical R&D. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and MS. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The product is light-sensitive (store away from light) and should be handled in a compatible environment for strong acids/organic solvents. Keep the container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.