Description

(3As,7As)-Octahydro-3H-Pyrrolo[3,4-C]Pyridin-3-One is a high-purity, advanced pharmaceutical intermediate belonging to the class of fused bicyclic heterocycles. This compound is of significant commercial importance for its role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in neurological and psychiatric therapeutic areas. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development and scale-up of novel drug candidates.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of complex drug molecules, especially those targeting the central nervous system.
• API Synthesis: Serves as a core scaffold for constructing active pharmaceutical ingredients with fused pyrrolo-pyridine structures.
• Medicinal Chemistry Research: Used in research and development (R&D) for structure-activity relationship (SAR) studies and lead optimization.
• Process Chemistry & Scale-Up: Employed in process development from laboratory scale to commercial manufacturing under GMP conditions.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Reference Standard: Can be supplied as a high-purity analytical standard for quality control and method validation.

Basic Information

Product Name	(3As,7As)-Octahydro-3H-Pyrrolo[3,4-C]Pyridin-3-One
CAS No.	868552-08-3
Molecular Formula	C7H12N2O
Molecular Weight	140.18 g/mol
Synonyms	(3aR,7aR)-Octahydro-1H-pyrrolo[3,4-c]pyridin-1-one; (3aR,7aR)-Hexahydro-1H-pyrrolo[3,4-c]pyridin-1-one; (3aR,7aR)-Octahydropyrrolo[3,4-c]pyridin-1-one; 1H-Pyrrolo[3,4-c]pyridin-1-one, hexahydro-, (3aR,7aR)-; (3aR,7aR)-1-Oxohexahydro-1H-pyrrolo[3,4-c]pyridine; (3aR,7aR)-Octahydro-1H-pyrrolo[3,4-c]pyridin-1-one; 868552-08-3; (3aR,7aR)-Octahydropyrrolo[3,4-c]pyridin-1-one
EINECS	Contact for details

Quality Control

Our (3As,7As)-Octahydro-3H-Pyrrolo[3,4-C]Pyridin-3-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production can adhere to cGMP guidelines for pharmaceutical applications, and stability data is available to support regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5% w/w
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.