Description

(3Ar,7Ar)-Rel-Octahydro-3H-Pyrrolo[3,4-C]Pyridin-3-One is a high-purity, advanced pharmaceutical intermediate belonging to the class of fused bicyclic heterocycles. This compound matters as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), offering a rigid, three-dimensional scaffold that is essential for modern drug discovery. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in developing new therapeutic agents, particularly within the central nervous system (CNS) and oncology research fields.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of novel drug candidates.
• Medicinal Chemistry Research: Serves as a versatile core structure for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• API Development: Used in the research and process development stages for active pharmaceutical ingredients targeting neurological disorders.
• Asymmetric Synthesis: Employed as a precursor or catalyst ligand in stereoselective synthesis due to its defined stereochemistry.
• Contract Research & Manufacturing (CRAM): Supplied to CDMOs for custom synthesis projects requiring high-purity, specialized intermediates.

Basic Information

Item	Detail
Product Name	(3Ar,7Ar)-Rel-Octahydro-3H-Pyrrolo[3,4-C]Pyridin-3-One
CAS No.	868551-69-3
Molecular Formula	C7H12N2O
Molecular Weight	140.18 g/mol
Synonyms	rel-(3aR,7aR)-Octahydro-1H-pyrrolo[3,4-c]pyridin-3-one; (3aR,7aR)-Octahydro-3H-pyrrolo[3,4-c]pyridin-3-one; 868551-69-3; Pyrrolopyridinone derivative; Fused bicyclic lactam; 3-Oxo-hexahydro-1H-pyrrolo[3,4-c]pyridine
EINECS	Contact for details

Quality Control

Our (3Ar,7Ar)-Rel-Octahydro-3H-Pyrrolo[3,4-C]Pyridin-3-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to ICH guidelines for stability and impurity profiling, supporting our commitment to supplying material suitable for research and development under cGMP standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and purity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.