Description

Ethyl 4-Methyl-5-Nitropicolinate is a high-purity, specialized organic compound serving as a critical building block in advanced chemical synthesis. Its value lies in its functionalized picolinate core, which provides a versatile scaffold for constructing complex molecules in pharmaceutical and agrochemical research. This intermediate is essential for R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), crop protection agents, and novel fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and pesticides, leveraging its nitropicolinate structure.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Fine Chemical Production: Employed in the manufacture of dyes, pigments, and other performance chemicals requiring a substituted picolinate moiety.
• Academic and Industrial Research: A valuable reagent for method development and exploring new chemical spaces in medicinal and synthetic chemistry.

Basic Information

Product Name	Ethyl 4-Methyl-5-Nitropicolinate
CAS No.	868551-26-2
Molecular Formula	C9H10N2O4
Molecular Weight	210.19 g/mol
Synonyms	Ethyl 4-methyl-5-nitropyridine-2-carboxylate; 5-Nitro-4-methylpicolinic acid ethyl ester; 2-Pyridinecarboxylic acid, 4-methyl-5-nitro-, ethyl ester; Ethyl 5-nitro-4-methylpicolinate; 4-Methyl-5-nitropicolinic acid ethyl ester; Ethyl 4-methyl-5-nitro-2-pyridinecarboxylate
EINECS	Contact for details

Quality Control

Our Ethyl 4-Methyl-5-Nitropicolinate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with your internal specifications and cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents. The container must be kept tightly closed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.