Description

2-Bromo-5-(4-Fluorophenyl)Pyridine is a high-value brominated and fluorinated heterocyclic building block essential for modern synthetic chemistry. This compound matters for its role as a key intermediate in the development of advanced materials and active pharmaceutical ingredients (APIs), where its unique halogenated structure enables precise molecular modifications. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecules.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound research.
• Agrochemical Synthesis: Used in the development of new-generation herbicides and fungicides, leveraging the bioactivity of the fluorophenylpyridine scaffold.
• Ligand & Catalyst Development: Serves as a building block for creating sophisticated ligands in transition metal catalysis and organometallic chemistry.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers or emissive materials for OLEDs.
• Chemical Biology Probes: Utilized to create tagged molecules or probes for studying biological pathways and protein interactions.
• Cross-Coupling Reactions: Acts as a versatile substrate in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.

Basic Information

Product Name	2-Bromo-5-(4-Fluorophenyl)Pyridine
CAS No.	868254-43-7
Molecular Formula	C11H7BrFN
Molecular Weight	252.08 g/mol
Synonyms	5-(4-Fluorophenyl)-2-bromopyridine; 2-Bromo-5-(p-fluorophenyl)pyridine; 2-Bromo-5-(4-fluorophenyl)pyridine; 868254-43-7; Pyridine, 2-bromo-5-(4-fluorophenyl)-; 4-Fluoro-2'-bromophenylpyridine; (4-Fluorophenyl)-5-bromopyridine
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-(4-Fluorophenyl)Pyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment, ensuring full traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.