Description

tert-Butyl 4-Amino-5-bromopyridine-2-carboxylate is a high-purity, multi-functional chemical building block essential for advanced organic synthesis. Its value lies in the strategic placement of reactive amino and bromo substituents on the pyridine core, enabling selective functionalization and complex heterocycle construction. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its halogenated pyridine structure.
• Ligand and Catalyst Development: Serves as a starting material for creating sophisticated nitrogen-containing ligands used in transition metal catalysis.
• Material Science Research: Employed in the synthesis of functionalized organic molecules for electronic materials and organic light-emitting diodes (OLEDs).
• Custom Synthesis & Contract Manufacturing: A critical building block for custom synthesis projects requiring precise, scalable modifications to the pyridine scaffold.
• Academic & R&D Laboratories: Used in medicinal chemistry programs for structure-activity relationship (SAR) studies and library synthesis.

Basic Information

Item	Details
Product Name	tert-Butyl 4-Amino-5-bromopyridine-2-carboxylate
CAS No.	868171-70-4
Molecular Formula	C10H13BrN2O2
Molecular Weight	273.13 g/mol
Synonyms	4-Amino-5-bromo-2-pyridinecarboxylic acid tert-butyl ester; 2-Pyridinecarboxylic acid, 4-amino-5-bromo-, 1,1-dimethylethyl ester; tert-Butyl 4-amino-5-bromopicolinate; 4-Amino-5-bromo-picolinic acid tert-butyl ester; 868171-70-4; TBABPC; 5-Bromo-4-aminopicolinic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-Amino-5-bromopyridine-2-carboxylate is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and scale-up. Comprehensive Certificates of Analysis (COA) with full traceability are provided to guarantee supply reliability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the original container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.