Description

3-Pyridinecarboxylic Acid, 1-(4-Fluorophenyl)-1,2-Dihydro-2-Oxo- is a high-purity, fluorinated heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its unique molecular scaffold, which combines a pyridinecarboxylic acid moiety with a fluorinated phenyl group, making it a versatile intermediate for constructing complex pharmacophores. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the discovery and development of new active ingredients. Its precise structure enables the exploration of novel chemical space in drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides, where the fluorine atom and heterocyclic core can enhance biological activity and environmental stability.
• Chemical Biology Probe Development: Employed as a scaffold for creating molecular probes to study enzyme function and protein-ligand interactions in biochemical pathways.
• Material Science Precursor: Acts as a monomer or functionalizing agent in the synthesis of specialized polymers and advanced organic materials with tailored electronic or optical properties.
• Academic & Contract Research: Supplied to universities and CROs (Contract Research Organizations) for fundamental research in medicinal chemistry and synthetic methodology development.

Basic Information

Item	Detail
Product Name	3-Pyridinecarboxylic Acid, 1-(4-Fluorophenyl)-1,2-Dihydro-2-Oxo-
CAS No.	868171-67-9
Molecular Formula	C12H8FNO3
Molecular Weight	233.20 g/mol
Synonyms	1-(4-Fluorophenyl)-1,2-dihydro-2-oxo-3-pyridinecarboxylic acid; 1-(4-Fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxylic acid; 3-Carboxy-1-(4-fluorophenyl)-2(1H)-pyridinone; 2-Oxo-1-(4-fluorophenyl)-1,2-dihydro-3-pyridinecarboxylic acid; Fluorophenyl DHPO carboxylic acid; 1-(p-Fluorophenyl)-1,2-dihydro-2-oxonicotinic acid
EINECS	Contact for details

Quality Control

Our 3-Pyridinecarboxylic Acid, 1-(4-Fluorophenyl)-1,2-Dihydro-2-Oxo- is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for research and pre-clinical development. A comprehensive Certificate of Analysis (COA) detailing purity (typically ≥95% by HPLC), residual solvents, and other critical parameters is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.