Description

3-Methoxymethyl-Piperidine-1-Carboxylic Acid tert-Butyl Ester is a high-purity, protected piperidine derivative serving as a critical building block in advanced organic synthesis. Its primary value lies in providing a versatile, reactive scaffold for constructing complex nitrogen-containing molecules, particularly in pharmaceutical research and development. This intermediate is essential for medicinal chemists and process development scientists working on new active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of piperidine-based drug candidates, including potential central nervous system (CNS) agents, receptor modulators, and enzyme inhibitors.
• Agrochemical Synthesis: Used in the research and development of novel pesticides, herbicides, and fungicides that incorporate a functionalized piperidine moiety.
• Chemical Research & Development: Serves as a versatile precursor in academic and industrial R&D labs for exploring new chemical entities and reaction pathways.
• Peptidomimetics & Bioactive Molecule Design: The protected amine and ester functionalities make it suitable for constructing peptide analogs and other bioactive scaffolds.
• Ligand & Catalyst Development: Employed in the synthesis of chiral ligands, organocatalysts, or metal complexes for asymmetric synthesis.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis houses producing bespoke intermediates for client projects.

Basic Information

Product Name	3-Methoxymethyl-Piperidine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	868065-26-3
Molecular Formula	C12H23NO3
Molecular Weight	229.32 g/mol
Synonyms	1-Boc-3-(methoxymethyl)piperidine; tert-Butyl 3-(methoxymethyl)piperidine-1-carboxylate; 3-(Methoxymethyl)-1-piperidinecarboxylic acid 1,1-dimethylethyl ester; 1,1-Dimethylethyl 3-(methoxymethyl)-1-piperidinecarboxylate; 1-N-Boc-3-methoxymethylpiperidine; N-Boc-3-methoxymethylpiperidine; Boc-3-methoxymethylpiperidine; 3-Methoxymethyl-1-piperidinecarboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and development use. We employ advanced analytical techniques, including HPLC, GC, NMR, and mass spectrometry, to verify identity, purity, and consistency for every batch. Certificates of Analysis (COA) are available upon request, providing full transparency on all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flames. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.