Description

5-Bromo-2-p-Tolylpyridine is a versatile brominated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and functional materials, where precise molecular architecture is critical. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular frameworks.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel drug candidates, particularly kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its pyridine core for bioactivity.
• Ligand Synthesis: Acts as a starting material for the preparation of specialized ligands used in catalysis and coordination chemistry.
• Material Science: Employed in the creation of organic electronic materials, such as those for OLEDs or conductive polymers.
• Chemical Biology: Utilized as a molecular probe or tag in bioconjugation and labeling studies.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions.

Basic Information

Product Name	5-Bromo-2-p-Tolylpyridine
CAS No.	867380-38-9
Molecular Formula	C₁₂H₁₀BrN
Molecular Weight	248.12 g/mol
Synonyms	5-Bromo-2-(4-methylphenyl)pyridine; 2-(4-Methylphenyl)-5-bromopyridine; 5-Bromo-2-(p-tolyl)pyridine; 5-Bromo-2-(4-tolyl)pyridine; 5-Bromo-2-(4-methylphenyl)pyridine; 867380-38-9; 5-Br-2-p-Tolylpyridine
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-p-Tolylpyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.