Description

4-Chloro-5-Methoxypyridin-2-Amine is a high-purity pyridine derivative building block of significant importance in advanced organic synthesis. This compound matters as a versatile and critical intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced crop protection agents and herbicides.
• Ligand and Catalyst Development: Serves as a precursor for creating novel ligands used in catalytic systems and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of organic electronic materials, dyes, and photoactive compounds.
• Chemical Biology Probes: Utilized as a scaffold for developing molecular probes and diagnostic agents.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	4-Chloro-5-Methoxypyridin-2-Amine
CAS No.	867131-26-8
Molecular Formula	C6H7ClN2O
Molecular Weight	158.59 g/mol
Synonyms	2-Amino-4-chloro-5-methoxypyridine; 4-Chloro-5-methoxy-2-pyridinamine; 5-Methoxy-4-chloropyridin-2-amine; 2-Pyridinamine, 4-chloro-5-methoxy-; 4-Chloro-5-methoxypyridin-2-ylamine; 4-Chloro-5-methoxy-2-aminopyridine
EINECS	Contact for details

Quality Control

Our 4-Chloro-5-Methoxypyridin-2-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider storage under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.