Description

3-Pyridinecarbonitrile, 6-Amino-5-Ethoxy- is a high-purity, advanced pharmaceutical intermediate characterized by its specific pyridine-based nitrile and amino-ethoxy substitution pattern. This compound matters as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), enabling the development of new therapeutic agents. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for process development and scale-up.

Application

• Pharmaceutical Intermediate: A key synthon for the research and production of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging its heterocyclic structure for biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in catalytic systems and metal-organic frameworks (MOFs).
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals and dyes.
• Academic and R&D: Utilized in university and corporate research laboratories for methodological studies and exploring new chemical reactions.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for clients.

Basic Information

Product Name	3-Pyridinecarbonitrile, 6-Amino-5-Ethoxy-
CAS No.	866889-20-5
Molecular Formula	C8H9N3O
Molecular Weight	163.18 g/mol
Synonyms	6-Amino-5-ethoxy-3-pyridinecarbonitrile; 5-Ethoxy-6-aminonicotinonitrile; 6-Amino-5-ethoxypyridine-3-carbonitrile; 3-Cyano-5-ethoxy-6-aminopyridine; 5-Ethoxy-6-amino-3-cyanopyridine; 6-Amino-5-ethoxy-nicotinonitrile; Nicotinonitrile, 6-amino-5-ethoxy-
EINECS	Contact for details

Quality Control

Our 3-Pyridinecarbonitrile, 6-Amino-5-Ethoxy- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support cGMP compliance for pharmaceutical applications and can tailor quality protocols to meet specific customer requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.