Description

Methyl 3-Amino-6-Bromo-5-(Trifluoromethyl)Picolinate is a high-purity, multi-functional heterocyclic building block of significant commercial interest. Its molecular architecture, featuring amino, bromo, and trifluoromethyl substituents on a picolinate core, makes it a versatile intermediate for synthesizing complex molecules. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients. Its reliable quality and consistent supply are critical for accelerating innovation in these high-value sectors.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system (CNS) disorders, oncology, and inflammation.
• Agrochemical Synthesis: Serves as a critical building block for developing advanced herbicides, fungicides, and insecticides, leveraging the bioactivity of the trifluoromethyl and bromo groups.
• Material Science Research: Used in the development of specialty chemicals, ligands for catalysis, and advanced organic electronic materials.
• Custom Synthesis & Contract Manufacturing: An essential starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.
• Academic & Industrial R&D: Employed in medicinal chemistry and chemical biology research for structure-activity relationship (SAR) studies and library synthesis.

Basic Information

Product Name	Methyl 3-Amino-6-Bromo-5-(Trifluoromethyl)Picolinate
CAS No.	866775-18-0
Molecular Formula	C8H6BrF3N2O2
Molecular Weight	299.05 g/mol
Synonyms	Methyl 3-Amino-6-Bromo-5-(trifluoromethyl)pyridine-2-carboxylate; 2-Pyridinecarboxylic acid, 3-amino-6-bromo-5-(trifluoromethyl)-, methyl ester; 3-Amino-6-bromo-5-(trifluoromethyl)picolinic acid methyl ester; 6-Bromo-5-(trifluoromethyl)-3-aminopicolinic acid methyl ester
EINECS	Contact for details

Quality Control

Every batch of Methyl 3-Amino-6-Bromo-5-(Trifluoromethyl)Picolinate is manufactured and tested under a strict quality management system. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.