Description

3-Nitro-5-Trifluoromethyl-Pyridine-2-Carbonitrile is a high-value, multi-functional heterocyclic building block designed for advanced chemical synthesis. This compound matters for its unique trifluoromethyl and nitrile functional groups, which are critical for modulating the physicochemical properties of target molecules, such as lipophilicity, metabolic stability, and binding affinity. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in kinase inhibitor and CNS-active compound libraries.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science Precursor: Serves as a building block for functionalized ligands and organic electronic materials.
• Chemical Research: Employed in academic and industrial R&D for exploring novel heterocyclic chemistry and reaction pathways.
• Fluorine Chemistry: An important reagent for introducing fluorine-containing motifs into complex molecular architectures.

Basic Information

Product Name	3-Nitro-5-Trifluoromethyl-Pyridine-2-Carbonitrile
CAS No.	866775-16-8
Molecular Formula	C7H2F3N3O2
Molecular Weight	217.10 g/mol
Synonyms	2-Cyano-3-nitro-5-(trifluoromethyl)pyridine; 5-(Trifluoromethyl)-3-nitropyridine-2-carbonitrile; 3-Nitro-5-(trifluoromethyl)picolinonitrile; 2-Pyridinecarbonitrile, 3-nitro-5-(trifluoromethyl)-; 866775-16-8
EINECS	Contact for details

Quality Control

Our 3-Nitro-5-Trifluoromethyl-Pyridine-2-Carbonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency suitable for research and scale-up. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.