Description

Methyl 3-Amino-5-Chloropicolinate is a high-purity, versatile heterocyclic building block essential for advanced organic synthesis. Its core value lies in its bifunctional picolinate ester structure, which serves as a critical intermediate for constructing complex molecules with high precision and yield. This compound is primarily needed by R&D and production teams in the pharmaceutical and agrochemical industries for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging its chlorinated pyridine core.
• Ligand and Catalyst Development: Serves as a valuable starting material for creating specialized chelating ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of functionalized polymers and organic electronic materials due to its modifiable amino and ester groups.
• Custom Synthesis and Contract Manufacturing: A fundamental building block for custom synthesis projects and scale-up production in fine chemical manufacturing.

Basic Information

Product Name	Methyl 3-Amino-5-Chloropicolinate
CAS No.	866775-11-3
Molecular Formula	C7H7ClN2O2
Molecular Weight	186.60 g/mol
Synonyms	Methyl 3-Amino-5-Chloro-2-pyridinecarboxylate; 5-Chloro-3-aminopicolinic Acid Methyl Ester; 3-Amino-5-chloropicolinic Acid Methyl Ester; Methyl 3-Amino-5-chloropyridine-2-carboxylate; 2-Pyridinecarboxylic acid, 3-amino-5-chloro-, methyl ester; 866775-11-3; 3-Amino-5-chloro-2-pyridinecarboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 3-Amino-5-Chloropicolinate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply and traceability for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong alkalis and incompatible organic solvents. The container must be kept tightly closed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.