Description

Methyl 5-Chloro-1,3,6-Trimethyl-1H-Pyrazolo[3,4-B]Pyridine-4-Carboxylate is a high-purity, advanced pharmaceutical intermediate crucial for modern drug discovery and development. This compound serves as a key building block in the synthesis of complex heterocyclic molecules, offering significant value in creating novel active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for developing new therapeutic agents and specialty chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its heterocyclic structure for biological activity.
• Fine Chemical Synthesis: Serves as a versatile building block for creating complex organic molecules in custom synthesis and process development.
• Academic & R&D: Employed in university and corporate research laboratories for methodological studies and the exploration of new chemical spaces.
• Contract Manufacturing (CMO): Supplied to contract manufacturing organizations for the production of client-specific compounds under cGMP conditions.

Basic Information

Item	Details
Product Name	Methyl 5-Chloro-1,3,6-Trimethyl-1H-Pyrazolo[3,4-B]Pyridine-4-Carboxylate
CAS No.	866769-80-4
Molecular Formula	C12H12ClN3O2
Molecular Weight	265.70 g/mol
Synonyms	5-Chloro-1,3,6-trimethyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid methyl ester; Methyl 5-chloro-1,3,6-trimethylpyrazolo[3,4-b]pyridine-4-carboxylate; 866769-80-4; 1H-Pyrazolo[3,4-b]pyridine-4-carboxylic acid, 5-chloro-1,3,6-trimethyl-, methyl ester
EINECS	Contact for details

Quality Control

Our production of Methyl 5-Chloro-1,3,6-Trimethyl-1H-Pyrazolo[3,4-B]Pyridine-4-Carboxylate adheres to stringent quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications. Our quality systems are designed to support both research and development (R&D) and current Good Manufacturing Practice (cGMP) production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.