Description

Pyridine, 2-Chloro-5-(Triethylsilyl)- (9Ci) is a specialized organosilicon-substituted pyridine derivative, serving as a valuable advanced synthetic intermediate and ligand precursor in modern organic synthesis. Its unique structure, combining a halogenated pyridine core with a triethylsilyl protecting group, makes it critical for constructing complex molecular architectures where precise steric and electronic control is required. This high-purity building block is essential for researchers and process chemists in pharmaceutical development, agrochemical research, and materials science.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and oncology.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its halogen and silicon functionality.
• Ligand for Catalysis: Serves as a precursor for N-heterocyclic carbene (NHC) ligands and other organometallic catalysts used in cross-coupling reactions.
• Material Science Precursor: Employed in the synthesis of organic semiconductors, liquid crystals, and metal-organic frameworks (MOFs) due to its rigid, functionalizable core.
• Organic Synthesis Reagent: Utilized in palladium-catalyzed reactions (e.g., Suzuki, Stille couplings) and as a protecting group strategy in multi-step syntheses.
• Chemical Research & Development: A high-value reagent for academic and industrial R&D labs exploring new synthetic methodologies and novel compound libraries.

Basic Information

Product Name	Pyridine, 2-Chloro-5-(Triethylsilyl)- (9Ci)
CAS No.	866755-17-1
Molecular Formula	C13H22ClNSi
Molecular Weight	255.86 g/mol
Synonyms	2-Chloro-5-(triethylsilyl)pyridine; 5-(Triethylsilyl)-2-chloropyridine; 2-Chloro-5-triethylsilylpyridine; (2-Chloropyridin-5-yl)triethylsilane; 866755-17-1; 2-Chloro-5-(triethylsilyl)pyridine (9CI); Pyridine, 2-chloro-5-(triethylsilyl)-
EINECS	Contact for details

Quality Control

Every batch of Pyridine, 2-Chloro-5-(Triethylsilyl)- (9Ci) is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.