Description

3-Bromo-5-Ethynylpyridine is a versatile and high-purity brominated pyridine derivative featuring a reactive ethynyl group. This compound is a critical pharmaceutical intermediate and organic building block for constructing complex molecular architectures. It is essential for researchers and manufacturers in medicinal chemistry, agrochemical development, and material science who require reliable, high-quality raw materials for advanced synthesis.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, leveraging its halogen and alkyne functionality.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the development of advanced polymers and functional organic materials.
• Ligand Synthesis for Catalysis: Employed to create sophisticated pyridine-based ligands for transition metal catalysis in fine chemical manufacturing.
• Bioconjugation and Probe Development: The ethynyl group enables click chemistry reactions (e.g., CuAAC) for labeling biomolecules and creating diagnostic probes.
• Chemical Research & Development: A versatile reagent for exploring novel organic reactions and synthesizing complex heterocyclic compounds in academic and industrial R&D.

Basic Information

Product Name	3-Bromo-5-Ethynylpyridine
CAS No.	866683-52-5
Molecular Formula	C7H4BrN
Molecular Weight	182.02 g/mol
Synonyms	5-Ethynyl-3-bromopyridine; 3-Bromo-5-ethynylpyridine; 3-Bromopyridin-5-ylacetylene; Pyridine, 3-bromo-5-ethynyl-; 5-(Bromo)ethynylpyridine; 3-Bromo-5-(ethynyl)pyridine
EINECS	Contact for details

Quality Control

Our 3-Bromo-5-Ethynylpyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is light-sensitive and should be stored away from direct light exposure. Keep container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.