Description

5-(tert-Butyl)Pyridin-2-Amine CAS NO 866620-21-5 is a high-purity, substituted pyridine derivative that serves as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of active pharmaceutical ingredients (APIs) and specialty agrochemicals. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and material science industries seeking to introduce sterically hindered amine functionality into complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the tert-butyl group enhances lipophilicity and biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating nitrogen-containing ligands used in transition metal catalysis for asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and metal-organic frameworks (MOFs) due to its rigid, aromatic structure.
• Chemical Research & Development: A valuable scaffold for medicinal chemistry and structure-activity relationship (SAR) studies in academic and industrial labs.

Basic Information

Product Name	5-(tert-Butyl)Pyridin-2-Amine
CAS No.	866620-21-5
Molecular Formula	C9H14N2
Molecular Weight	150.22 g/mol
Synonyms	2-Amino-5-tert-butylpyridine; 5-tert-Butyl-2-pyridinamine; 5-(1,1-Dimethylethyl)-2-pyridinamine; 2-Pyridinamine, 5-(1,1-dimethylethyl)-; 5-tert-Butylpyridin-2-amine; 5-(tert-Butyl)-2-aminopyridine; 5-tert-Butyl-2-aminopyridine; 2-Amino-5-(tert-butyl)pyridine
EINECS	Contact for details

Quality Control

Our 5-(tert-Butyl)Pyridin-2-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, GC for residual solvents, and NMR/IR for structural confirmation, to ensure compliance with customer specifications and industry standards. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available for every shipment upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.