Description

Methyl 6-Hydroxy-5-Oxo-7-(1-Phenylallyl)-1,2,3,5-Tetrahydroindolizine-8-Carboxylate is a high-purity, advanced pharmaceutical intermediate with the CAS number 866393-54-6. This compound is a critical building block in the synthesis of complex heterocyclic molecules, offering significant value in research and development. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers for the development of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel indolizine-based drug candidates for therapeutic applications.
• Organic Synthesis Research: Used as a versatile scaffold in academic and industrial research for constructing complex polycyclic frameworks.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to develop new compounds with potential biological activity.
• Fine Chemical Production: Acts as a specialized intermediate in the multi-step synthesis of high-value, low-volume specialty chemicals.
• Contract Research & Development (CRO/CMO): Supplied to organizations engaged in custom synthesis and process development for clients.
• Chemical Reference Standard: Can be utilized as a high-purity analytical standard for method development and quality control in related syntheses.

Basic Information

Product Name	Methyl 6-Hydroxy-5-Oxo-7-(1-Phenylallyl)-1,2,3,5-Tetrahydroindolizine-8-Carboxylate
CAS No.	866393-54-6
Molecular Formula	C20H19NO4
Molecular Weight	337.37 g/mol
Synonyms	Methyl 6-hydroxy-5-oxo-7-(1-phenylallyl)-1,2,3,5-tetrahydro-8H-indolizine-8-carboxylate; 8H-Indolizine-8-carboxylic acid, 1,2,3,5-tetrahydro-6-hydroxy-5-oxo-7-(1-phenyl-2-propen-1-yl)-, methyl ester; 866393-54-6; Methyl 6-hydroxy-5-oxo-7-(1-phenylprop-2-en-1-yl)-1,2,3,5-tetrahydroindolizine-8-carboxylate; 7-(1-Phenylallyl)-6-hydroxy-5-oxo-1,2,3,5-tetrahydroindolizine-8-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 6-Hydroxy-5-Oxo-7-(1-Phenylallyl)-1,2,3,5-Tetrahydroindolizine-8-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.