Description

1H-Pyrrolo[2,3-B]Pyridine, 5-Fluoro-1-[(4-Methylphenyl)Sulfonyl]- is a high-value, fluorinated heterocyclic sulfonamide building block of significant interest in advanced organic synthesis. This compound matters for its role as a critical intermediate in the development of novel pharmaceutical agents, particularly kinase inhibitors and other targeted therapeutics. It is primarily needed by research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: Serves as a key scaffold in the synthesis of potential drug candidates, especially kinase inhibitors for oncology and inflammatory diseases.
• Agrochemical Research: Used in the discovery and development of new active ingredients for crop protection.
• Chemical Biology: Employed as a molecular probe or tool compound for studying biological pathways and target validation.
• Material Science: Potential precursor for the synthesis of specialty polymers or organic electronic materials due to its fused heterocyclic structure.
• Custom Synthesis & Scale-Up: Supplied for custom synthesis projects requiring this specific fluorinated pyrrolopyridine derivative.

Basic Information

Product Name	1H-Pyrrolo[2,3-B]Pyridine, 5-Fluoro-1-[(4-Methylphenyl)Sulfonyl]-
CAS No.	866318-99-2
Molecular Formula	C14H11FN2O2S
Molecular Weight	290.31 g/mol
Synonyms	5-Fluoro-1-(p-tolylsulfonyl)-1H-pyrrolo[2,3-b]pyridine; 5-Fluoro-1-tosyl-1H-pyrrolo[2,3-b]pyridine; 1-(4-Methylphenyl)sulfonyl-5-fluoro-1H-pyrrolo[2,3-b]pyridine; 5-Fluoro-1-[(4-methylphenyl)sulfonyl]-1H-pyrrolo[2,3-b]pyridine; 866318-99-2; 5-Fluoro-1-tosyl-7-azaindole; 5-Fluoro-1H-pyrrolo[2,3-b]pyridine, 1-[(4-methylphenyl)sulfonyl]-
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[2,3-B]Pyridine, 5-Fluoro-1-[(4-Methylphenyl)Sulfonyl]- is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) with detailed chromatographic data (HPLC, GC) and spectroscopic confirmation are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.