Description

5-Chloro-3-Ethynylpyridin-2-Amine is a high-purity, multi-functional pyridine derivative featuring both chloro and ethynyl substituents, making it a versatile and valuable building block in advanced chemical synthesis. Its molecular structure is engineered to serve as a critical intermediate for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors, receptor antagonists, and other small-molecule drug candidates.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a building block for creating novel ligands in transition metal catalysis and organometallic chemistry.
• Material Science Research: Employed in the development of organic semiconductors, conductive polymers, and advanced organic frameworks.
• Chemical Biology Probes: Utilized for creating tagged molecules and probes for studying biological pathways and target engagement.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	5-Chloro-3-Ethynylpyridin-2-Amine
CAS No.	866318-88-9
Molecular Formula	C7H5ClN2
Molecular Weight	152.58 g/mol
Synonyms	2-Amino-5-chloro-3-ethynylpyridine; 3-Ethynyl-5-chloropyridin-2-amine; 5-Chloro-3-ethynyl-2-pyridinamine; 5-Chloro-3-ethynyl-2-aminopyridine; 866318-88-9; 5-Chloro-3-ethynylpyridin-2-ylamine
EINECS	Contact for details

Quality Control

Every batch of 5-Chloro-3-Ethynylpyridin-2-Amine is manufactured and tested under strict quality management systems to ensure consistency and reliability for your critical applications. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards. Certificates of Analysis (COA) with detailed specifications are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.