Description

4(1H)-Quinazolinone, 5,7-Dichloro-2-[(Dimethylamino)Methyl]-8-Methoxy- (9Ci) is a high-purity, functionalized quinazolinone derivative, a privileged scaffold in medicinal chemistry. This compound matters as a critical pharmaceutical intermediate and research chemical for the development of novel bioactive molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and life science industries for drug discovery programs targeting various therapeutic areas.

Application

• Pharmaceutical Intermediate: Serves as a key building block for the synthesis of potential drug candidates, particularly kinase inhibitors and other small-molecule therapeutics.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its modifiable quinazolinone core.
• Chemical Biology Probes: Acts as a precursor for developing tool compounds to study biological pathways and protein functions.
• Agrochemical Research: Employed in the discovery of new active ingredients for crop protection products.
• Academic & Institutional R&D: Utilized in universities and research institutes for fundamental organic synthesis and heterocyclic chemistry studies.
• Custom Synthesis & Contract Manufacturing: A starting material for the custom synthesis of complex molecules for client-specific projects.

Basic Information

Product Name	4(1H)-Quinazolinone, 5,7-Dichloro-2-[(Dimethylamino)Methyl]-8-Methoxy- (9Ci)
CAS No.	866244-59-9
Molecular Formula	C₁₂H₁₃Cl₂N₃O₂
Molecular Weight	302.16 g/mol
Synonyms	5,7-Dichloro-2-[(dimethylamino)methyl]-8-methoxy-4(1H)-quinazolinone; 5,7-Dichloro-8-methoxy-2-[(dimethylamino)methyl]quinazolin-4(1H)-one; 2-[(Dimethylamino)methyl]-5,7-dichloro-8-methoxy-1,4-dihydroquinazolin-4-one; 866244-59-9; 5,7-Dichloro-8-methoxy-2-(N,N-dimethylaminomethyl)-4(1H)-quinazolinone
EINECS	Contact for details

Quality Control

Our high-purity 4(1H)-Quinazolinone derivative is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.