Description

4,5,6,7-Tetrahydropyrazolo[1,5-A]Pyridin-5-Amine Dihydrochloride is a high-purity, heterocyclic amine derivative supplied as a dihydrochloride salt. This compound serves as a critical pharmaceutical intermediate and building block in advanced organic synthesis, enabling the development of novel active ingredients. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Research: Used as a building block for developing new pesticides and herbicides with specific biological activity.
• Chemical Synthesis: Serves as a versatile nitrogen-containing heterocycle for constructing complex molecular architectures in medicinal chemistry.
• Bioconjugation & Probe Development: The amine functionality allows for conjugation, useful in creating biochemical probes and labeled compounds for research.
• Academic & Industrial R&D: Employed in research laboratories for method development and exploring new synthetic pathways.

Basic Information

Product Name	4,5,6,7-Tetrahydropyrazolo[1,5-A]Pyridin-5-Amine Dihydrochloride
CAS No.	866216-20-8
Molecular Formula	C7H12N4 · 2HCl
Molecular Weight	241.12 g/mol (Free base: 152.20 g/mol)
Synonyms	5-Amino-4,5,6,7-tetrahydropyrazolo[1,5-a]pyridine dihydrochloride; 4,5,6,7-Tetrahydro-5-aminopyrazolo[1,5-a]pyridine dihydrochloride; 5-Amino-4,5,6,7-tetrahydropyrazolo[1,5-a]pyridine hydrochloride (1:2); Pyrazolo[1,5-a]pyridin-5-amine, 4,5,6,7-tetrahydro-, dihydrochloride; THPP-5-Amine dihydrochloride
EINECS	Contact for details

Quality Control

Our 4,5,6,7-Tetrahydropyrazolo[1,5-A]Pyridin-5-Amine Dihydrochloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, impurity profile, and identity confirmation. Our quality system is designed to meet the stringent requirements of pharmaceutical R&D and GMP-guided production environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.