Description

Ethyl (E)-3-(4-(Trifluoromethoxy)Phenyl)Acrylate is a high-value fluorinated acrylate ester building block, prized for its unique trifluoromethoxy-substituted aromatic structure. This compound is essential for introducing lipophilicity, metabolic stability, and electronic properties into advanced molecular architectures. It is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for CNS, anti-inflammatory, and antiviral applications.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides where the trifluoromethoxy group enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated components for electronic display and lighting technologies.
• Polymer & Resin Modification: Incorporated as a specialty monomer to impart specific chemical resistance, surface energy, or optical properties to advanced polymers.
• Chemical Research & Development: A versatile building block for Suzuki, Heck, and other cross-coupling reactions in medicinal and process chemistry.
• Fluorinated Dye & Pigment Precursor: Used in the development of specialty colorants with enhanced lightfastness and solubility properties.

Basic Information

Product Name	Ethyl (E)-3-(4-(Trifluoromethoxy)Phenyl)Acrylate
CAS No.	866207-69-4
Molecular Formula	C₁₂H₁₁F₃O₃
Molecular Weight	260.21 g/mol
Synonyms	(E)-Ethyl 3-[4-(Trifluoromethoxy)phenyl]acrylate; Ethyl (E)-3-[4-(Trifluoromethoxy)phenyl]propenoate; 2-Propenoic acid, 3-[4-(trifluoromethoxy)phenyl]-, ethyl ester, (E)-; 4-Trifluoromethoxycinnamic acid ethyl ester; Ethyl 4-(Trifluoromethoxy)cinnamate; Ethyl (E)-3-(4-Trifluoromethoxyphenyl)acrylate
EINECS	Contact for details

Quality Control

Our Ethyl (E)-3-(4-(Trifluoromethoxy)Phenyl)Acrylate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports your R&D and scale-up processes with reliable, traceable material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.