Description

1-(4-Fluorobenzoyl)Tetrahydro-4(1H)-Pyridinone is a high-purity fluorinated heterocyclic building block of significant interest in advanced organic synthesis. This compound serves as a critical intermediate for the development of novel pharmaceutical candidates and fine chemicals, offering a versatile scaffold for structural diversification. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries engaged in drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the fluorobenzoyl moiety for enhanced biological activity and metabolic stability.
• Organic Synthesis Reagent: Employed as a versatile precursor for constructing complex nitrogen-containing heterocycles via reactions such as alkylation, acylation, and ring-closure transformations.
• Material Science Research: Investigated as a monomer or functional additive in the development of advanced polymers and specialty materials with tailored properties.
• Chemical Biology Probe: Utilized in medicinal chemistry to create molecular probes for studying enzyme function and biological pathways.

Basic Information

Product Name	1-(4-Fluorobenzoyl)Tetrahydro-4(1H)-Pyridinone
CAS No.	866144-28-7
Molecular Formula	C12H12FNO2
Molecular Weight	221.23 g/mol
Synonyms	1-(4-Fluorobenzoyl)piperidin-4-one; 4-Piperidinone, 1-(4-fluorobenzoyl)-; 1-(4-Fluorobenzoyl)-4-piperidinone; 1-(p-Fluorobenzoyl)piperidin-4-one; 4-Fluoro-N-(4-oxopiperidin-1-yl)benzamide; Tetrahydro-4(1H)-pyridinone, 1-(4-fluorobenzoyl)-; 866144-28-7
EINECS	Contact for details

Quality Control

Our 1-(4-Fluorobenzoyl)Tetrahydro-4(1H)-Pyridinone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.