Description

1-(4-Methylbenzyl)-2-Oxo-4-(2-Thienyl)-1,2-Dihydro-3-Pyridinecarbonitrile is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound matters as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), enabling the development of targeted therapies. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating new molecular entities.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly in therapeutic areas requiring complex heterocyclic scaffolds.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its thienyl and pyridine motifs for biological activity.
• Material Science: Potential building block for organic electronic materials, such as organic semiconductors or light-emitting diodes (OLEDs), due to its conjugated system.
• Chemical Biology: Acts as a molecular probe or a core structure in the design of enzyme inhibitors and receptor modulators for biological studies.
• Academic & Contract Research: Employed in university and CRO (Contract Research Organization) laboratories for methodological development and discovery chemistry projects.
• Custom Synthesis: Basis for the custom manufacturing of specialized fine chemicals and bespoke intermediates for client-specific applications.

Basic Information

Product Name	1-(4-Methylbenzyl)-2-Oxo-4-(2-Thienyl)-1,2-Dihydro-3-Pyridinecarbonitrile
CAS No.	866136-73-4
Molecular Formula	C18H14N2OS
Molecular Weight	306.38 g/mol
Synonyms	4-(Thiophen-2-yl)-1-(4-methylbenzyl)-2-oxo-1,2-dihydropyridine-3-carbonitrile; 1-[(4-Methylphenyl)methyl]-2-oxo-4-(2-thienyl)-1,2-dihydro-3-pyridinecarbonitrile; 3-Cyano-1-(4-methylbenzyl)-4-(thiophen-2-yl)pyridin-2(1H)-one; 1-(4-Methylbenzyl)-4-(2-thienyl)-2-oxo-1,2-dihydro-3-pyridinecarbonitrile; 866136-73-4
EINECS	Contact for details

Quality Control

Our 1-(4-Methylbenzyl)-2-Oxo-4-(2-Thienyl)-1,2-Dihydro-3-Pyridinecarbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure compliance with client specifications and industry standards. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.