Description

Methyl 2-(4-Bromophenyl)Imidazo[1,2-A]Pyridine-6-Carboxylate is a high-purity, advanced pharmaceutical intermediate with a distinct molecular architecture. This compound matters for its critical role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex heterocyclic scaffolds. Pharmaceutical R&D teams and fine chemical manufacturers need this precise intermediate to develop and scale up production of next-generation drug candidates targeting a range of diseases.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the multi-step synthesis of complex drug molecules, especially those containing the imidazopyridine core.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic agents with improved efficacy and safety profiles.
• API Development: Integral to the process development and scale-up of new Active Pharmaceutical Ingredients (APIs) for preclinical and clinical trials.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and target validation.
• Contract Research & Manufacturing (CRAM): Supplied to CDMOs and CROs engaged in custom synthesis projects for pharmaceutical clients.
• Academic Research: Utilized in university and institutional laboratories for pioneering research in organic synthesis and drug discovery methodologies.

Basic Information

Product Name	Methyl 2-(4-Bromophenyl)Imidazo[1,2-A]Pyridine-6-Carboxylate
CAS No.	866133-69-9
Molecular Formula	C15H11BrN2O2
Molecular Weight	331.17 g/mol
Synonyms	Methyl 2-(4-bromophenyl)imidazo[1,2-a]pyridine-6-carboxylate; 6-Carbomethoxy-2-(4-bromophenyl)imidazo[1,2-a]pyridine; 2-(4-Bromophenyl)imidazo[1,2-a]pyridine-6-carboxylic acid methyl ester; Imidazo[1,2-a]pyridine-6-carboxylic acid, 2-(4-bromophenyl)-, methyl ester; Methyl 2-(p-bromophenyl)imidazo[1,2-a]pyridine-6-carboxylate; CAS 866133-69-9
EINECS	Contact for details

Quality Control

Our production of Methyl 2-(4-Bromophenyl)Imidazo[1,2-A]Pyridine-6-Carboxylate adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity, essential for pharmaceutical applications. All material is characterized and released against comprehensive specifications, including identity confirmation, assay, and impurity profiling. A Certificate of Analysis (COA) detailing all test results is provided with each shipment. Our quality system supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and atmospheric contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any individual impurity ≤ 0.5% Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.