Description

Methyl 3-(2-Fluorophenyl)-3-[(2,2,2-Trifluoroacetyl)Amino]Propanoate is a high-value, fluorinated organic building block designed for advanced chemical synthesis. This compound matters for its role as a key intermediate in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is needed by research chemists and process development scientists working on new active ingredients, where its unique fluorine-containing structure enables precise modulation of biological activity and physicochemical properties.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, where fluorination enhances stability and bioavailability.
• Chemical Synthesis Building Block: Serves as a versatile synthon for constructing complex molecules in medicinal chemistry and material science research.
• Process Chemistry & Scale-Up: Employed in route scouting and optimization for the commercial production of fluorinated active pharmaceutical ingredients (APIs).

Basic Information

Product Name	Methyl 3-(2-Fluorophenyl)-3-[(2,2,2-Trifluoroacetyl)Amino]Propanoate
CAS No.	866050-44-4
Molecular Formula	C12H11F4NO3
Molecular Weight	293.22 g/mol
Synonyms	Methyl 3-amino-3-(2-fluorophenyl)propanoate trifluoroacetamide; 3-[(2,2,2-Trifluoroacetyl)amino]-3-(2-fluorophenyl)propanoic acid methyl ester; 2-Fluorophenylalanine derivative, N-TFA methyl ester; Methyl 3-(2-fluorophenyl)-3-(2,2,2-trifluoroacetamido)propanoate; N-(2,2,2-Trifluoroacetyl)-3-(2-fluorophenyl)-β-alanine methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 3-(2-Fluorophenyl)-3-[(2,2,2-Trifluoroacetyl)Amino]Propanoate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. All products undergo rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.