Description

Ethyl 2,2-Bis(4-Chlorobenzyl)-3-Oxobutanoate is a specialized organic ester compound featuring a β-ketoester core flanked by chlorobenzyl groups. This molecular architecture makes it a valuable intermediate in advanced organic synthesis, particularly for constructing complex pharmacophores and agrochemical active ingredients. It is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries for the development of new active compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders or possessing anti-inflammatory properties.
• Agrochemical Synthesis: Serves as a precursor in the development of new-generation herbicides, fungicides, or plant growth regulators, leveraging the bioactivity of the chlorobenzyl motifs.
• Organic Synthesis Reagent: Used in academic and industrial R&D for constructing complex molecules via reactions such as alkylation, condensation, or cyclization.
• Chemical Research: Employed as a standard or reference material in analytical method development and structure-activity relationship (SAR) studies.
• Material Science Precursor: Potential intermediate for synthesizing specialized monomers or ligands used in advanced material applications.

Basic Information

Product Name	Ethyl 2,2-Bis(4-Chlorobenzyl)-3-Oxobutanoate
CAS No.	866040-55-3
Molecular Formula	C20H20Cl2O3
Molecular Weight	379.28 g/mol
Synonyms	Ethyl 2,2-Bis(p-chlorobenzyl)-3-oxobutanoate; 2,2-Bis(4-chlorobenzyl)-3-oxobutanoic Acid Ethyl Ester; Ethyl 2,2-Di(4-chlorobenzyl)acetoacetate; 3-Oxobutanoic Acid, 2,2-Bis(4-chlorophenyl)methyl-, Ethyl Ester; Acetoacetic Acid, 2,2-Bis(p-chlorobenzyl)-, Ethyl Ester
EINECS	Contact for details

Quality Control

Our Ethyl 2,2-Bis(4-Chlorobenzyl)-3-Oxobutanoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets exacting R&D and process chemistry standards. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.