Description

Methyl 5-((tert-Butyldimethylsilyl)Oxy)-2-Methylbenzoate is a high-purity, protected benzoate derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its value lies in the tert-butyldimethylsilyl (TBDMS) protecting group, which offers exceptional stability under a wide range of reaction conditions, enabling precise multi-step synthesis. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors, particularly for constructing complex molecules where selective deprotection is required.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds containing substituted benzoic acid motifs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Serves as a precursor for dyes, pigments, and specialty polymers requiring protected phenolic functionalities.
• Academic & R&D Laboratories: A valuable reagent for methodological development in organic synthesis and catalysis studies.
• Material Science Research: Potential monomer or modifier in the development of novel organic electronic materials and liquid crystals.

Basic Information

Product Name	Methyl 5-((tert-Butyldimethylsilyl)Oxy)-2-Methylbenzoate
CAS No.	866028-37-7
Molecular Formula	C15H24O3Si
Molecular Weight	280.44 g/mol
Synonyms	Methyl 5-[(tert-Butyldimethylsilyl)oxy]-2-methylbenzoate; 2-Methyl-5-[(tert-butyldimethylsilyl)oxy]benzoic Acid Methyl Ester; Methyl 2-Methyl-5-[(tert-butyldimethylsilyl)oxy]benzoate; 5-(tert-Butyldimethylsiloxy)-2-methylbenzoic Acid Methyl Ester; Methyl 5-(TBDMS-oxy)-2-methylbenzoate; Benzoic acid, 5-[(1,1-dimethylethyl)dimethylsilyl]oxy]-2-methyl-, methyl ester; TBDMS-protected Methyl 2-Methyl-5-hydroxybenzoate
EINECS	Contact for details

Quality Control

Our Methyl 5-((tert-Butyldimethylsilyl)Oxy)-2-Methylbenzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP and ISO 9001 compliant production for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.