Description

(Z)-2-(3-Methoxyphenyl)-3-(6-Piperidino-3-Pyridinyl)-2-Propenenitrile is a high-purity, advanced pharmaceutical intermediate designed for research and development. This compound is valued for its role as a key building block in the synthesis of novel therapeutic agents, particularly within medicinal chemistry. It is essential for pharmaceutical companies, contract research organizations (CROs), and academic institutions focused on developing new drug candidates.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs) for various therapeutic areas.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new drug molecules.
• Kinase Inhibitor Development: Serves as a core scaffold or intermediate in the design and synthesis of potential kinase inhibitors.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and GMP production.
• Biochemical Research: Employed as a tool compound in biochemical assays to study specific biological pathways and target interactions.
• Academic & Institutional R&D: Utilized in university and research institute laboratories for exploratory synthetic chemistry and drug discovery projects.

Basic Information

Product Name	(Z)-2-(3-Methoxyphenyl)-3-(6-Piperidino-3-Pyridinyl)-2-Propenenitrile
CAS No.	866019-91-2
Molecular Formula	C20H21N3O
Molecular Weight	319.40 g/mol
Synonyms	(Z)-2-(3-Methoxyphenyl)-3-(6-(piperidin-1-yl)pyridin-3-yl)acrylonitrile; 2-(3-Methoxyphenyl)-3-[6-(1-piperidinyl)-3-pyridinyl]-2-propenenitrile, (Z)-; (Z)-3-(6-(Piperidin-1-yl)pyridin-3-yl)-2-(3-methoxyphenyl)acrylonitrile; Propenenitrile, 2-(3-methoxyphenyl)-3-[6-(1-piperidinyl)-3-pyridinyl]-, (Z)-; 866019-91-2; (Z)-2-(3-Methoxyphenyl)-3-(6-piperidin-1-ylpyridin-3-yl)prop-2-enenitrile
EINECS	Contact for details

Quality Control

Our (Z)-2-(3-Methoxyphenyl)-3-(6-Piperidino-3-Pyridinyl)-2-Propenenitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.