Description

1-[3-Chloro-5-(Trifluoromethyl)-2-Pyridinyl]-1-Ethanol is a high-value pyridine derivative and a crucial chiral building block in advanced organic synthesis. Its molecular structure, featuring both chloro and trifluoromethyl substituents, makes it an essential intermediate for creating complex molecules with specific biological activity. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in areas requiring fluorinated compounds.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of novel fluorinated organic materials and liquid crystals.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	1-[3-Chloro-5-(Trifluoromethyl)-2-Pyridinyl]-1-Ethanol
CAS No.	866018-09-9
Molecular Formula	C8H7ClF3NO
Molecular Weight	225.59 g/mol
Synonyms	1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)ethanol; 2-(1-Hydroxyethyl)-3-chloro-5-(trifluoromethyl)pyridine; α-(3-Chloro-5-trifluoromethyl-2-pyridyl)ethanol; 1-(3-Chloro-5-trifluoromethyl-2-pyridinyl)ethanol; 866018-09-9; 1-(3-Chloro-5-(trifluoromethyl)-2-pyridyl)ethan-1-ol
EINECS	Contact for details

Quality Control

Our 1-[3-Chloro-5-(Trifluoromethyl)-2-Pyridinyl]-1-Ethanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the high standards required for research and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee (Typical)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.