Description

(2S,3S,5S)-5-(Acetoxymethyl)-Tetrahydrofuran-2,3-Diyl Diacetate is a high-purity, stereochemically defined carbohydrate derivative. This compound matters as a crucial chiral intermediate and building block in the synthesis of complex pharmaceutical molecules, offering precise control over the final product's biological activity. It is primarily needed by research institutions and manufacturers in the pharmaceutical and fine chemical industries for developing nucleoside analogs, antiviral agents, and other advanced therapeutics.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of nucleoside-based antiviral and anticancer drugs.
• Pro-drug Development: Used to create masked or protected forms of active pharmaceutical ingredients (APIs) to improve bioavailability or stability.
• Carbohydrate Chemistry: Serves as a protected sugar derivative for constructing complex oligosaccharides or glycoconjugates.
• Chemical Research: A valuable reagent in academic and industrial R&D for exploring new synthetic pathways and catalytic processes.
• Fine Chemical Synthesis: Employed in the production of specialty chemicals requiring high stereochemical purity.

Basic Information

Product Name	(2S,3S,5S)-5-(Acetoxymethyl)-Tetrahydrofuran-2,3-Diyl Diacetate
CAS No.	865853-43-6
Molecular Formula	C12H18O8
Molecular Weight	290.26 g/mol
Synonyms	1,2,5-Tri-O-acetyl-β-D-ribofuranose; 1,2,5-Tri-O-acetyl-β-D-ribose; β-D-Ribofuranose 1,2,5-triacetate; (2S,3S,5S)-5-(Acetoxymethyl)tetrahydrofuran-2,3-diyl diacetate; 1,2,5-Tri-O-acetyl-D-ribofuranose; Triacetyl-β-D-ribofuranose; D-Ribofuranose, 1,2,5-triacetate
EINECS	Contact for details

Quality Control

Our (2S,3S,5S)-5-(Acetoxymethyl)-Tetrahydrofuran-2,3-Diyl Diacetate is manufactured under strict quality management systems. We offer material suitable for research and development use, with purity levels typically exceeding 97% (by HPLC). All products undergo rigorous analytical testing, including chiral purity verification, to ensure batch-to-batch consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.