Description

5-Bromo-3H-Spiro[Benzofuran-2,4'-Piperidin]-3-One is a high-value, spirocyclic organic compound featuring a fused benzofuran and piperidine structure, serving as a critical synthetic intermediate. Its unique molecular architecture makes it an essential building block for constructing complex molecules in advanced pharmaceutical research and development. This compound is primarily targeted at medicinal chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates targeting central nervous system (CNS) disorders, such as antipsychotics or neuropathic pain treatments.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Agrochemical Development: Serves as a building block for creating novel active ingredients with potential herbicidal or insecticidal properties.
• Chemical Biology Probe Synthesis: Employed in the development of molecular probes for studying biological pathways and protein functions.
• Material Science Research: Investigated as a monomer or precursor for creating specialty polymers with unique optical or electronic properties.

Basic Information

Product Name	5-Bromo-3H-Spiro[Benzofuran-2,4'-Piperidin]-3-One
CAS No.	865758-52-7
Molecular Formula	C12H12BrNO2
Molecular Weight	282.14 g/mol
Synonyms	5-Bromospiro[benzofuran-2,4'-piperidin]-3-one; 5-Bromo-3-oxo-3H-spiro[benzofuran-2,4'-piperidine]; 865758-52-7; 5-Bromo-3H-spiro[1-benzofuran-2,4'-piperidin]-3-one; 5-Bromospiro(benzofuran-2,4'-piperidin)-3-one; 5-Bromo-3H-spiro[benzofuran-2,4'-piperidin]-3-one; 5-Bromo-3H-spiro[2-benzofuran-1,4'-piperidin]-3-one
EINECS	Contact for details

Quality Control

Our 5-Bromo-3H-Spiro[Benzofuran-2,4'-Piperidin]-3-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.